{"id":1222,"date":"2024-01-31T05:10:39","date_gmt":"2024-01-31T05:10:39","guid":{"rendered":"https:\/\/forlovenew.azurewebsites.net\/?page_id=1222"},"modified":"2024-12-20T04:30:05","modified_gmt":"2024-12-20T04:30:05","slug":"leukemia-in-children","status":"publish","type":"page","link":"https:\/\/rvch.rainbowforlove.org\/?page_id=1222","title":{"rendered":"\u767d\u8840\u75c5\uff08\u6982\u8ff0\uff09"},"content":{"rendered":"\n<h3>\u767d\u8840\u75c5 \u79d1\u666e\u77e5\u8bc6<\/h3>\n\n\n\n<p>\u767d\u8840\u75c5\u662f\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u6700\u5e38\u89c1\u7684\u764c\u75c7\uff0c\u51e0\u4e4e\u5360\u4e86\u4e09\u5206\u4e4b\u4e00\u3002 \u5927\u90e8\u5206\u513f\u7ae5\u767d\u8840\u75c5\u662f\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u6027\u767d\u8840\u75c5\uff08ALL\uff09\uff0c\u7b80\u79f0\u6025\u6dcb\u3002 \u5176\u4f59\u5927\u90e8\u5206\u75c5\u4f8b\u662f\u6025\u6027\u9ad3\u7ec6\u80de\u6027\u767d\u8840\u75c5\uff08AML\uff09\uff0c\u4e5f\u53eb\u6025\u975e\u6dcb\u3002 \u6162\u6027\u767d\u8840\u75c5\u5728\u513f\u7ae5\u4e2d\u662f\u7f55\u89c1\u7684\u3002<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons has-custom-font-size has-small-font-size\">\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1222\" style=\"background-color:#4971a2\">\u6982\u8ff0&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1227\" style=\"color:#000000a8\">\u75c5\u56e0&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1235\" style=\"color:#000000a8\">\u98ce\u9669\u56e0\u7d20&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1243\" style=\"color:#000000a8\">\u9884\u9632&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1247\" style=\"color:#000000a8\">\u5c31\u533b&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1252\" style=\"color:#000000a8\">\u6cbb\u7597&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1267\" style=\"color:#000000a8\">\u9884\u540e&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1254\" style=\"color:#000000a8\">\u65e5\u5e38\u62a4\u7406&gt;<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link has-white-background-color has-text-color has-background wp-element-button\" href=\"\/?page_id=1273\" style=\"color:#000000a8\">\u53c2\u8003\u8d44\u6599&gt;<\/a><\/div>\n<\/div>\n\n\n\n<h1>\u513f\u7ae5\u767d\u8840\u75c5-\u6982\u8ff0<\/h1>\n\n\n\n<blockquote class=\"wp-block-quote\">\n<p><font _mstmutation=\"1\" _msttexthash=\"617754761\" _msthash=\"2792\">\u672c\u7bc7\u6587\u7ae0\u8f6c\u8f7d\u4e8e\u5f69\u8679\u6709\u7231\u513f\u7ae5\u4e4b\u5bb6<\/font><font _mstmutation=\"1\" _msttexthash=\"881050274\" _msthash=\"2792\">\u516c\u76ca<\/font><font _mstmutation=\"1\" _msttexthash=\"5390463\" _msthash=\"2792\">\u4f19\u4f34<\/font><font _mstmutation=\"1\" _msttexthash=\"617754761\" _msthash=\"2792\">\u300c<\/font><font _mstmutation=\"1\" _msttexthash=\"270654969\" _msthash=\"2792\">\u5411\u65e5\u8475\u513f\u7ae5<\/font><font _mstmutation=\"1\" _msttexthash=\"325725478\" _msthash=\"2792\">\u300d<\/font><font _mstmutation=\"1\" _msttexthash=\"270654969\" _msthash=\"2792\">\uff0c\u6b22\u8fce\u5404\u4f4d\u5bb6\u957f\u5b66\u4e60\u4e86\u89e3\uff0c\u5e0c\u671b\u5bf9\u60a3\u513f\u7684\u7167\u62a4\u8fc7\u7a0b\u6709\u6240\u5e2e\u52a9\u3002<\/font><font _mstmutation=\"1\"><\/font><\/p>\n<cite><font _mstmutation=\"1\"><\/font><\/cite><\/blockquote>\n\n\n\n<h4><strong _msttexthash=\"9243\">1.<\/strong><strong>\u603b\u8ff0<\/strong><\/h4>\n\n\n\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u6982\u8ff0\uff1a\u513f\u7ae5\u767d\u8840\u75c5\u662f\u4e00\u7c7b\u9020\u8840\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u6027\u75be\u75c5\uff0c\u662f\u6211\u56fd\u513f\u7ae5\u53d1\u75c5\u7387\u6700\u9ad8\u7684\u6076\u6027\u80bf\u7624\u3002\u5c0f\u513f\u65f6\u671f\u53d1\u751f\u7684\u767d\u8840\u75c5\u591a\u4e3a\u6025\u6027\u767d\u8840\u75c5\uff0c\u867d\u7136\u75c5\u60c5\u53d1\u5c55\u8fc5\u901f\uff0c\u4f46\u662f\u5982\u53ca\u65f6\u660e\u786e\u8bca\u65ad\u3001\u91c7\u7528\u9002\u5f53\u7684\u6cbb\u7597\u624b\u6bb5\uff0c\u5f80\u5f80\u90fd\u80fd\u53d6\u5f97\u6ee1\u610f\u7597\u6548\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u8868\u73b0\uff1a\u513f\u7ae5\u767d\u8840\u75c5\u53ef\u8868\u73b0\u4e3a\u4e0d\u540c\u7a0b\u5ea6\u7684\u8d2b\u8840\u3001\u51fa\u8840\u3001\u611f\u67d3\u53d1\u70ed\u4ee5\u53ca\u809d\u3001\u813e\u3001\u6dcb\u5df4\u7ed3\u80bf\u5927\u548c\u9aa8\u9abc\u75bc\u75db\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6cbb\u7597\uff1a\u513f\u7ae5\u767d\u8840\u75c5\u662f\u4e00\u5927\u7c7b\u75be\u75c5\u7684\u603b\u79f0\uff0c\u4e0d\u540c\u5206\u578b\u7684\u767d\u8840\u75c5\u6cbb\u7597\u65b9\u6848\u4e5f\u5404\u6709\u4e0d\u540c\u3002\u60a3\u513f\u5bb6\u957f\u5e94\u79ef\u6781\u914d\u5408\u533b\u751f\u786e\u8bca\uff0c\u4ee5\u4fbf\u91c7\u7528\u9002\u5f53\u7684\u6cbb\u7597\u624b\u6bb5\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u9884\u540e\uff1a\u4e0d\u540c\u7c7b\u578b\u7684\u767d\u8840\u75c5\u9884\u540e\u4e5f\u5404\u6709\u4e0d\u540c\uff0c\u4f8b\u5982\u513f\u7ae5\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\uff08\u4e5f\u79f0M3\u578b\uff09\u3001\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08ALL\uff09\u4e94\u5e74\u751f\u5b58\u7387\u53ef\u4ee5\u8fbe\u523090%\u4ee5\u4e0a\uff1b\u800c\u513f\u7ae5\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u4e94\u5e74\u751f\u5b58\u7387\u4e3a60%-70%\u3002<\/p>\n\n\n\n<h4><strong>2.&nbsp;<\/strong><strong>\u75be\u75c5\u5b9a\u4e49<\/strong><\/h4>\n\n\n\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u513f\u7ae5\u767d\u8840\u75c5\u662f\u4e00\u7c7b\u9020\u8840\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u6027\u75be\u75c5\uff0c\u662f\u6211\u56fd\u513f\u7ae5\u53d1\u75c5\u7387\u6700\u9ad8\u7684\u6076\u6027\u80bf\u7624\uff0c\u7ea6\u5360\u6240\u6709\u513f\u7ae5\u6076\u6027\u80bf\u7624\u76841\/3\u3002\u767d\u8840\u75c5\u7684\u53d1\u751f\u662f\u7531\u4e8e\u9aa8\u9ad3\u4e2d\u7684\u9020\u8840\u7ec6\u80de\u51fa\u73b0\u5f02\u5e38\u7684\u5206\u88c2\u589e\u6b96\uff0c\u5f62\u6210\u767d\u8840\u75c5\u7ec6\u80de\uff0c\u4ece\u800c\u5bfc\u81f4\u767d\u8840\u75c5\u3002<\/p>\n\n\n\n<h4><strong>3.&nbsp;<\/strong><strong>\u6d41\u884c\u75c5\u5b66<\/strong><\/h4>\n\n\n\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u6839\u636e2013\u5e74\u7684\u7edf\u8ba1\uff0c\u6211\u56fd5\u5c81\u4ee5\u4e0b\u513f\u7ae5\u767d\u8840\u75c5\u53d1\u75c5\u7387\u4e3a11.81\/10\u4e07\uff0c5-10\u5c81\u513f\u7ae5\u53d1\u75c5\u7387\u4e3a4.61\/10\u4e07\uff0c10-15\u5c81\u7684\u53d1\u75c5\u7387\u4e3a4.50\/10\u4e07\uff0c15-20\u5c81\u7684\u53d1\u75c5\u7387\u4e3a4.75\/10\u4e07\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08acute lymphoblastic leukemia, ALL\uff09\u662f\u5728\u513f\u7ae5\u4e2d\u6700\u5e38\u89c1\u7684\u767d\u8840\u75c5\uff0c\u7ea6\u5360\u513f\u7ae5\u6025\u6027\u767d\u8840\u75c5\u768470%\u5de6\u53f3\u3002\u4e2d\u56fd\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0815\u5c81\u4ee5\u4e0b\uff09\u53d1\u75c5\u7387\u7ea6\u4e3a3-3.5\/10\u4e07\uff1b\u5982\u6269\u5927\u81f318\u5c81\u4ee5\u4e0b\uff0c\u6bcf\u5e74\u65b0\u53d1\u60a3\u513f1\u4e07\u4eba\u5de6\u53f3\u3002\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u53d1\u75c5\u7684\u9ad8\u5cf0\u5e74\u9f84\u4e00\u822c\u57283-5\u5c81\uff0c\u4ee5\u540e\u9010\u6e10\u4e0b\u964d\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u513f\u7ae5\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08acute myeloid leukemia, AML\uff09\u7684\u53d1\u751f\u7387\u4ec5\u6b21\u4e8e\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u5360\u513f\u7ae5\u6025\u6027\u767d\u8840\u75c5\u768420%\u5de6\u53f3\u3002\u5176\u4e2d\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\uff08acute promyelocytic leukemia, APL\uff09\u5360\u513f\u7ae5\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u768410%\u5de6\u53f3\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6b64\u5916\uff0c\u513f\u7ae5\u6162\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08chronic myeloid leukemia, CML\uff09\u8f83\u4e3a\u5c11\u89c1\uff0c\u5360\u513f\u7ae5\u767d\u8840\u75c5\u76843~5%\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\uff08juvenile myelomonocytic leukemia, JMML\uff09\u4e3b\u8981\u53d1\u751f\u4e8e4\u5c81\u4ee5\u4e0b\u7684\u5a74\u5e7c\u513f\uff0c\u4e2d\u4f4d\u786e\u8bca\u5e74\u9f84\u4e3a2\u5c81\uff0c\u7537\u5b69\u53d1\u75c5\u7387\u9ad8\u4e8e\u5973\u5b69\u3002\u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u5360\u513f\u7ae5\u767d\u8840\u75c5\u76841~2%\u3002<\/p>\n\n\n\n<h4><strong>4.&nbsp;<\/strong><strong>\u57fa\u672c\u7c7b\u578b<\/strong><\/h4>\n\n\n\n<p><strong>\uff081\uff09\u75be\u75c5\u5206\u7c7b<\/strong><br>&nbsp; &nbsp; &nbsp; &nbsp; \u767d\u8840\u75c5\u901a\u5e38\u6309\u8d77\u75c5\u7f13\u6025\u5206\u6210\u6025\u6027\u767d\u8840\u75c5\u548c\u6162\u6027\u767d\u8840\u75c5\u3002\u6025\u6027\u767d\u8840\u75c5\u7ec6\u80de\u5206\u5316\u8f83\u5dee\uff0c\u4ee5\u505c\u6ede\u5728\u65e9\u671f\u9636\u6bb5\u7684\u539f\u59cb\u53ca\u65e9\u5e7c\u7ec6\u80de\u4e3a\u4e3b\uff0c\u75be\u75c5\u53d1\u5c55\u8fc5\u901f\u3002\u6162\u6027\u767d\u8840\u75c5\u7ec6\u80de\u5206\u5316\u8f83\u597d\uff0c\u4ee5\u5e7c\u7a1a\u6216\u6210\u719f\u7ec6\u80de\u4e3a\u4e3b\uff0c\u53d1\u5c55\u7f13\u6162\uff0c\u75c5\u7a0b\u8f83\u957f\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u767d\u8840\u75c5\u8fd8\u53ef\u4ee5\u6309\u589e\u751f\u7684\u8840\u7ec6\u80de\u7c7b\u578b\u5212\u5206\u6210\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u548c\u9ad3\u7cfb\u767d\u8840\u75c5\u3002\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u4f1a\u5f71\u54cd\u5f62\u6210\u6dcb\u5df4\u6216\u6dcb\u5df4\u7ec4\u7ec7\u7684\u6dcb\u5df4\u6837\u7ec6\u80de\u3002\u6dcb\u5df4\u7ec4\u7ec7\u6784\u6210\u514d\u75ab\u7cfb\u7edf\u3002\u9ad3\u7cfb\u767d\u8840\u75c5\u4f1a\u5f71\u54cd\u9ad3\u7cfb\u7ec6\u80de\uff0c\u5305\u62ec\u7ea2\u7ec6\u80de\uff0c\u7c92\u7ec6\u80de\u3001\u5355\u6838\u7ec6\u80de\u548c\u5de8\u6838\u7ec6\u80de\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u7efc\u5408\u8d77\u6765\uff0c\u513f\u7ae5\u767d\u8840\u75c5\u4e3b\u8981\u5305\u62ec\u4ee5\u4e0b\u51e0\u5927\u7c7b\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08acute lymphoblastic leukemia, ALL\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; \u4e3b\u8981\u8d77\u6e90\u4e8e\u9aa8\u9ad3\u5185\u7684\u524d\u4f53B\u6216\u524d\u4f53T\u7ec6\u80de\uff08\u767d\u7ec6\u80de\u7684\u4e3b\u8981\u79cd\u7c7b\uff09\u7684\u5f02\u5e38\u589e\u751f\u548c\u805a\u96c6\u3002\u5f02\u5e38\u589e\u6b96\u6291\u5236\u4e86\u6b63\u5e38\u9020\u8840\u529f\u80fd\uff0c\u6700\u7ec8\u5f71\u54cd\u5230\u7ea2\u7ec6\u80de\uff0c\u7c92\u7ec6\u80de\u548c\u8840\u5c0f\u677f\u7684\u6b63\u5e38\u4ea7\u751f\uff0c\u5bfc\u81f4\u8d2b\u8840\uff0c\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u548c\u8840\u5c0f\u677f\u51cf\u5c11\uff1b\u80bf\u7624\u7ec6\u80de\u4e5f\u53ef\u4e5f\u4fb5\u72af\u9ad3\u5916\u7ec4\u7ec7\uff0c\u5982\u8111\u819c\u3001\u6027\u817a\u3001\u80f8\u817a\u3001\u809d\u3001\u813e\uff0c\u6dcb\u5df4\u7ed3\u6216\u9aa8\u7ec4\u7ec7\u7b49\uff0c\u5f15\u8d77\u76f8\u5e94\u75c5\u53d8\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6309\u7167\u6cd5\u3001\u7f8e\u3001\u82f1\u5206\u578b\u7cfb\u7edf\uff08French\u2013American\u2013British classification systems\uff0cFAB\uff09\uff0c\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u53ef\u6839\u636e\u9aa8\u9ad3\u7ec6\u80de\u5f62\u6001\u5b66\u5206\u4e3aL1\u3001L2 \u548cL3 \u4e09\u578b\u3002\u4f46\u76ee\u524d\u8fd9\u79cd\u5206\u578b\u5df2\u4e0d\u518d\u4f5c\u4e3a\u5371\u9669\u5ea6\u5206\u7ec4\u7684\u4f9d\u636e\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6839\u636e\u6dcb\u5df4\u7ec6\u80de\u514d\u75ab\u5206\u578b\uff0c\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u53ef\u5206\u4e3a\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u6025\u6027B\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08B-ALL\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u6839\u636e\u767d\u8840\u75c5\u7ec6\u80de\u5206\u5316\u9636\u6bb5\u4e0d\u540c\uff0c\u6025\u6027B\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u4e3b\u8981\u5206\u4e3a\u65e9\u671f\u524dB\u3001\u666e\u901aB\u3001\u524dB\u3001 \u6210\u719fB \u56db\u79cd\u7c7b\u578b\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u6025\u6027T\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08T-ALL\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u6839\u636e\u767d\u8840\u75c5\u7ec6\u80de\u5206\u5316\u9636\u6bb5\u4e0d\u540c\uff0c\u6025\u6027T\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u4e3b\u8981\u5206\u4e3a\u65e9\u524dT\u3001 \u76ae\u8d28T\u53ca\u9ad3\u8d28T \u56db\u79cd\u7c7b\u578b\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u4e34\u5e8a\u4e0a\uff0c\u533b\u751f\u901a\u5e38\u4f1a\u5bf9\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u8fdb\u884cMICM\u5206\u578b\uff0c\u5373\u5728\u7ec6\u80de\u5f62\u6001\u5b66\uff08morphology, M\uff09\u3001\u514d\u75ab\u8868\u578b\uff08immunology, I\uff09\u3001\u7ec6\u80de\u9057\u4f20\u5b66\uff08cytogenetics, C\uff09\u3001\u5206\u5b50\u751f\u7269\u5b66\uff08molecular biology\uff09\u8fd9\u56db\u4e2a\u65b9\u9762\u5bf9\u60a3\u513f\u7684\u9aa8\u9ad3\u53ca\u8840\u6db2\u6837\u672c\u8fdb\u884c\u68c0\u6d4b\uff0c\u4ee5\u4fbf\u8fdb\u884c\u7cbe\u786e\u7684\u8bca\u65ad\u5206\u578b\uff0c\u5e2e\u52a9\u786e\u5b9a\u540e\u7eed\u6cbb\u7597\u65b9\u6848\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u513f\u7ae5\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08acute myeloid leukemia, AML\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u4e5f\u79f0\u4e3a\u6025\u6027\u9ad3\u7ec6\u80de\u767d\u8840\u75c5\u3001\u6025\u6027\u7c92\u7ec6\u80de\u6027\u767d\u8840\u75c5\uff0c\u6216\u6025\u6027\u975e\u6dcb\u5df4\u7ec6\u80de\u6027\u767d\u8840\u75c5\u3002\u8fd9\u4e9b\u60a3\u8005\u7684\u9aa8\u9ad3\u4f1a\u751f\u4ea7\u5927\u91cf\u4e0d\u6b63\u5e38\u7684\u7ea2\u7ec6\u80de\u3001\u6216\u767d\u7ec6\u80de\u3001\u6216\u5de8\u6838\u7ec6\u80de\u3002\u5982\u679c\u4e0d\u6cbb\u7597\uff0c\u5f80\u5f80\u8fc5\u901f\u6076\u5316\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6839\u636e\u7ec6\u80de\u5f62\u6001\u5b66\uff0c\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u53ef\u4ee5\u6309\u7167FAB\u5206\u578b\u6807\u51c6\u5206\u4e3aM0\u3001M1\uff5eM7\u578b\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u548c\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u7c7b\u4f3c\uff0c\u4e34\u5e8a\u4e0a\u533b\u751f\u4e5f\u4f1a\u5bf9\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u8fdb\u884cMICM\u5206\u578b\uff0c\u4ee5\u4fbf\u8fdb\u884c\u7cbe\u786e\u7684\u8bca\u65ad\u5206\u578b\uff0c\u5e2e\u52a9\u786e\u5b9a\u540e\u7eed\u6cbb\u7597\u65b9\u6848\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u9700\u8981\u7279\u522b\u6307\u51fa\u7684\u662f\uff0c\u513f\u7ae5\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u5305\u542b\u4e86\u7ea610%\u7684\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\u3002\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\u901a\u5e38\u4f34\u6709\u4e25\u91cd\u7684\u51dd\u8840\u5f02\u5e38\u3001\u8868\u73b0\u4e3a\u4e0d\u540c\u7a0b\u5ea6\u7684\u51fa\u8840\uff0c\u75c5\u7a0b\u8fdb\u5c55\u975e\u5e38\u5feb\uff0c\u6240\u4ee5\u6709\u4e13\u95e8\u7684\u6cbb\u7597\u8003\u91cf\u3002\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\u4f9d\u636eFAB\u5206\u578b\u5c5e\u4e8e\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5M3\u578b\uff0c\u6709\u7279\u5f81\u6027\u7684\u7b2c15\u53f7\u548c\u7b2c17\u53f7\u67d3\u8272\u4f53\u6613\u4f4d\uff08\u8bb0\u4f5ct(15;17)\uff09\uff0c\u53ef\u4ee5\u68c0\u51fa\u8fd9\u79cd\u67d3\u8272\u4f53\u6613\u4f4d\u5bfc\u81f4\u7684PML-RAR\u03b1\u878d\u5408\u57fa\u56e0\u9633\u6027\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u513f\u7ae5\u6162\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08chronic myeloid leukemia, CML\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; \u6162\u6027\u9ad3\u6027\u767d\u8840\u75c5\u4e5f\u79f0\u4e3a\u6162\u6027\u7c92\u7ec6\u80de\u6027\u767d\u8840\u75c5\uff08chronic granulocytic leukemia\uff0cCGL\uff09\u3002 \u8fd9\u79cd\u7c7b\u578b\u7684\u767d\u8840\u75c5\u8f83\u5c11\u89c1\u4e8e\u513f\u7ae5\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\uff08juvenile myelomonocytic leukemia, JMML\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; \u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u662f\u513f\u7ae5\u65e9\u671f\u9636\u6bb5\u4e00\u79cd\u5c11\u89c1\u7684\u7279\u6b8a\u7c7b\u578b\u9ad3\u7cfb\u767d\u8840\u75c5\uff0c\u4e3b\u8981\u53d1\u751f\u4e8e\u5a74\u5e7c\u513f\u3002\u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u65e2\u4e0d\u5c5e\u4e8e\u6162\u6027\u767d\u8840\u75c5\uff0c\u4e5f\u4e0d\u5c5e\u4e8e\u6025\u6027\u767d\u8840\u75c5\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\uff08WHO\uff09\u5c06\u5176\u5206\u7c7b\u4e3a\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\uff0f\u9aa8\u9ad3\u589e\u6b96\u6027\u80bf\u7624\u3002\u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u4ee5\u7c92\u5355\u6838\u7ec6\u80de\u5f02\u5e38\u589e\u751f\u548c\u5206\u5316\u53ca\u5668\u5b98\u6d78\u6da6\u4e3a\u663e\u8457\u7279\u5f81\uff0c\u9884\u540e\u4e0d\u7406\u60f3\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u56fd\u9645\u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u5de5\u4f5c\u5c0f\u7ec4\u786e\u5b9a\u5e7c\u5e74\u578b\u7c92\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u8bca\u65ad\u6807\u51c6\u5982\u4e0b\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cfI. \u987b\u540c\u65f6\u6ee1\u8db3\u4ee5\u4e0b\u6240\u6709\u6807\u51c6\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf BCR-ABL\u878d\u5408\u57fa\u56e0\u9634\u6027<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u5355\u6838\u7ec6\u80de\u7edd\u5bf9\u8ba1\u6570\u22651.0\u00d7109 \/L<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u813e\u5927<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u9aa8\u9ad3\u6216\u5916\u5468\u8840\u5e7c\u7a1a\u7ec6\u80de\u6bd4\u4f8b&lt;20%<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf II. \u987b\u6ee1\u8db3\u4ee5\u4e0b\u81f3\u5c111\u9879\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5b58\u5728RAS\u6216PTPN11\u57fa\u56e0\u4f53\u7ec6\u80de\u7a81\u53d8<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u7b26\u54081\u578b\u795e\u7ecf\u7ea4\u7ef4\u7624\u75c5\u8bca\u65ad\u6807\u51c6\uff0c\u6216\u5b58\u5728NF1\u57fa\u56e0\u7a81\u53d8<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf 7\u53f7\u67d3\u8272\u4f53\u5355\u4f53\uff08\u6b63\u5e38\u4eba\u67092\u67617\u53f7\u67d3\u8272\u4f53\uff09<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf III. \u987b\u6ee1\u8db3\u4ee5\u4e0b\u81f3\u5c111\u9879\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u767d\u7ec6\u80de\u226510\u00d7109 \/L<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u51fa\u73b0\u9ad3\u7cfb\u5e7c\u7a1a\u7ec6\u80de<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u8840\u7ea2\u86cb\u767dF\u5347\u9ad8<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5b58\u5728\u96647\u53f7\u67d3\u8272\u4f53\u5355\u4f53\u5916\u7684\u5176\u4ed6\u514b\u9686\u6027\u7ec6\u80de\u9057\u4f20\u5b66\u9057\u4f20<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u7c92\u7ec6\u80de-\u5de8\u566c\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\u9ad8\u654f\u611f\u6027<br><strong>\uff082\uff09\u75be\u75c5\u5206\u671f<\/strong><br>&nbsp; &nbsp; &nbsp; &nbsp; \u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u548c\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u901a\u5e38\u53ea\u8fdb\u884c\u5371\u9669\u5ea6\u5206\u7ec4\uff0c\u4e0d\u5206\u671f\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u513f\u7ae5\u6162\u6027\u9ad3\u6027\u767d\u8840\u75c5\u6839\u636e\u75be\u75c5\u7684\u8fdb\u5c55\u60c5\u51b5\uff0c\u53ef\u5206\u671f\u4e3a\u6162\u6027\u671f\u3001\u52a0\u901f\u671f\u548c\u6025\u53d8\u671f\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u6162\u6027\u671f\u8bca\u65ad\u6807\u51c6\u4e3a\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u4f4e\u70ed\u3001\u4e4f\u529b\u3001\u591a\u6c57\u3001\u4f53\u91cd\u51cf\u8f7b\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u767d\u7ec6\u80de\u8ba1\u6570\u5347\u9ad8\uff0c\u4e3b\u8981\u4e3a\u4e2d\u6027\u3001\u665a\u5e7c\u7c92\u7ec6\u80de\u548c\u6746\u72b6\u6838\u7c92\u7ec6\u80de\uff0c\u539f\u59cb\u7c92\u7ec6\u80de\uff0b\u65e9\u5e7c\u7c92\u7ec6\u80de\uff1c10%\uff0c\u55dc\u9178\u548c\u55dc\u78b1\u7c92\u7ec6\u80de\u589e \u591a\uff0c\u6709\u5c11\u91cf\u6709\u6838\u7ea2\u7ec6\u80de\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u9aa8\u9ad3\u589e\u751f\u660e\u663e\u81f3\u6d3b\u8dc3\uff0c\u7c92\u7cfb\u4e3a\u4e3b\uff0c\u539f\u59cb\u7ec6\u80de\uff1c10%\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u8d39\u57ce\u67d3\u8272\u4f53\u6216BCR-ABL\u878d\u5408\u57fa\u56e0\u9633\u6027\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u7c92\u7ec6\u80de-\u5de8\u566c\u7ec6\u80de\u96c6\u843d\u5f62\u6210\u5355\u4f4d\uff08CFU-GM\uff09\u57f9\u517b\u96c6\u843d\u6216\u96c6\u7c07\u8f83\u6b63\u5e38\u660e\u663e\u589e\u52a0\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u52a0\u901f\u671f\uff0c\u7b26\u5408\u4e0b\u5217\u4efb\u4f55\u4e00\u9879\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u6216\u9aa8\u9ad3\u4e2d\u539f\u59cb\u7ec6\u80de\u536010-19%\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u55dc\u78b1\u7c92\u7ec6\u80de\u226520%\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u6301\u7eed\u8840\u5c0f\u677f\u51cf\u5c11\uff08PLT&lt; 100\u00d7109\/L\uff09\u6216\u6cbb\u7597\u65e0\u6548\u7684\u6301\u7eed\u6027\u8840\u5c0f\u677f\u589e\u591a\uff08PLT &gt;1000\u00d7109\/L\uff09\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u8fdb\u884c\u6027\u813e\u810f\u589e\u5927\u6216\u767d\u7ec6\u80de\u8ba1\u6570\u589e\u9ad8\uff0c\u6cbb\u7597\u65e0\u6548\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u9664\u8d39\u57ce\u67d3\u8272\u4f53\u9633\u6027\uff08Ph+\uff09\u5916\uff0c\u53c8\u51fa\u73b0\u5176\u4ed6\u67d3\u8272\u4f53\u5f02\u5e38\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u7c92\u7ec6\u80de-\u5de8\u566c\u7ec6\u80de\u96c6\u843d\u5f62\u6210\u5355\u4f4d\uff08CFU-CM\uff09\u57f9\u517b\uff0c\u96c6\u7c07\u589e\u52a0\u800c\u96c6\u843d\u51cf\u5c11\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u9aa8\u9ad3\u6d3b\u68c0\u663e\u793a\u80f6\u539f\u7ea4\u7ef4\u589e\u751f\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u6025\u53d8\u671f\uff0c\u7b26\u5408\u4e0b\u5217\u4efb\u4f55\u4e00\u9879\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5916\u5468\u8840\u6216\u9aa8\u9ad3\u4e2d\u539f\u59cb\u7ec6\u80de\u226520%\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u51fa\u73b0\u9ad3\u5916\u6d78\u6da6\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u9aa8\u9ad3\u6d3b\u68c0\u53ef\u89c1\u539f\u59cb\u7ec6\u80de\u6210\u7247\u6216\u805a\u96c6\u6210\u7c07\u3002<br><strong>\uff083\uff09\u75be\u75c5\u5371\u9669\u5ea6\u5206\u7ec4<\/strong><br>&nbsp; &nbsp; &nbsp; &nbsp; \u5728\u4e34\u5e8a\u4e0a\uff0c\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u548c\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u4f1a\u8fdb\u884c\u5371\u9669\u5ea6\u5206\u7ec4\uff0c\u4ee5\u4fbf\u8fdb\u884c\u5206\u5c42\u6cbb\u7597\u3002\u5206\u7ec4\u901a\u5e38\u901a\u8fc7\u68c0\u6d4b\u60a3\u513f\u7684\u8840\u6db2\u3001\u9aa8\u9ad3\uff0c\u548c\u6dcb\u5df4\u7ed3\u6216\u8111\u810a\u6db2 (CSF\uff09\u6837\u54c1\u4e2d\u767d\u8840\u75c5\u7ec6\u80de\u7684\u9057\u4f20\u5b66\u548c\u5206\u5b50\u751f\u7269\u5b66\u7279\u5f81\uff0c\u4ee5\u53ca\u5fae\u5c0f\u6b8b\u7559\u75c5\u53d8\uff08MRD\uff09\u6765\u786e\u5b9a\u3002\u56fd\u9645\u4e0a\u4e0d\u540c\u7684\u4e2d\u5fc3\u5206\u7ec4\u6807\u51c6\u7565\u6709\u5dee\u5f02\uff0c\u4e14\u968f\u7740\u68c0\u6d4b\u6280\u672f\u7684\u63d0\u9ad8\u5206\u7ec4\u6807\u51c6\u4f1a\u4e0d\u65ad\u66f4\u65b0\u5b8c\u5584\u3002\u5371\u9669\u5ea6\u5206\u7ec4\u5bf9\u786e\u5b9a\u6cbb\u7597\u65b9\u6848\u6709\u7740\u91cd\u8981\u7684\u4f5c\u7528\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u76ee\u524d\u6700\u57fa\u672c\u7684\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u7684\u5371\u9669\u5ea6\u5206\u7ec4<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u7b26\u5408\u4ee5\u4e0b\u6240\u6709\u6761\u4ef6\u7684\u60a3\u513f\uff0c\u5206\u4e3a\u4f4e\u5371\u7ec4\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf 1\u5c81\u6216\u4ee5\u4e0a\u4e14\u4e0d\u6ee110\u5c81\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u767d\u7ec6\u80de\u8ba1\u6570\u4f4e\u4e8e50\u00d7109\/L\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u8bf1\u5bfc\u5316\u7597\u7b2c15-19\u5929\uff0c\u6216\u8bf1\u5bfc\u5316\u7597\u7b2c33-45 \u5929\uff0c\u9aa8\u9ad3\u7ec6\u80de\u5f62\u6001\u5b66\u68c0\u67e5\u7ed3\u679c\u4e3aM1\u72b6\u6001\uff08\u539f\u59cb\u6dcb\u5df4\u7ec6\u80de+\u5e7c\u7a1a\u6dcb\u5df4\u7ec6\u80de\uff1c5\uff05\uff09\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u8bf1\u5bfc\u6cbb\u7597\u7b2c15-33\u5929\u5fae\u5c0f\u6b8b\u7559\u75c5\u53d8\uff08MRD\uff09\uff1c1\u00d710-2 \uff0c\u4e14\u5de9\u56fa\u6cbb\u7597\u524dMRD\uff1c1\u00d710-4\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u6ee1\u8db3\u4ee5\u4e0b\u6761\u4ef6\u81f3\u5c11\u4e00\u9879\u7684\u60a3\u513f\uff0c\u5206\u4e3a\u4e2d\u5371\u7ec4\uff1a<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5e74\u9f8410 \u5c81\u6216\u4ee5\u4e0a\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u521d\u8bca\u65f6\u6700\u9ad8\u767d\u7ec6\u80de\u8ba1\u6570\u9ad8\u4e8e50\u00d7109\/L\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u5b58\u5728\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6216\u777e\u4e38\u6d78\u6da6\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf t(1;19) (E2A-PBX1)\u67d3\u8272\u4f53\u91cd\u6392\u3002<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; \u25cf \u7b2c15-19\u5929\u9aa8\u9ad3\u7ec6\u80de\u5f62\u6001\u5b66\u68c0\u67e5\u7ed3\u679c\u4e3aM2\uff085%\u2264\u539f\u59cb\u6dcb\u5df4\u7ec6\u80de+\u5e7c\u7a1a\u6dcb\u5df4\u7ec6\u80de\uff1c20%\uff09\uff0c\u4e14\u7b2c33-45\u5929\u9aa8\u9aa8\u9ad3\u7ec6\u80de\u5f62\u6001\u5b66\u68c0\u67e5\u7ed3\u679c\u4e3aM1\u3002<\/p>\n\n\n\n<p> \u25cf \u8d39\u57ce\u67d3\u8272\u4f53\u9633\u6027\uff08Ph+\uff09\u3002 <br> \u25cfiAMP21\u67d3\u8272\u4f53\u53d8\u5f02\u3002 <br> \u25cf \u7c7b\u578b\u4e3a\u6025\u6027T\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u3002 <br> \u25cf \u8bf1\u5bfc\u6cbb\u7597\u7b2c15-19\u5929\uff0c1\u00d710-3\u2264MRD\uff1c1\u00d710-1\uff1b\u6216\u8bf1\u5bfc\u6cbb\u7597\u540e\uff08\u7b2c33-45\u5929\uff09\uff0c1\u00d710-4\u2264MRD\uff1c1\u00d710-2\uff1b\u6216\u5de9\u56fa\u6cbb\u7597\u524d\uff0cMRD\uff1c1\u00d710-4\u3002 <br> \u25cf \u6ee1\u8db3\u4ee5\u4e0b\u6761\u4ef6\u81f3\u5c11\u4e00\u9879\u7684\u60a3\u513f\uff0c\u5206\u4e3a\u9ad8\u5371\u7ec4\uff1a<br> \u25cf \u60a3\u513f\u5e74\u9f84\u5c0f\u4e8e1\u5c81\u3002 <br> \u25cf \u7b2c15-19\u5929\u9aa8\u9ad3\u7ec6\u80de\u5f62\u6001\u5b66\u68c0\u67e5\u7ed3\u679c\u4e3aM3\u72b6\u6001\uff08\u539f\u59cb\u6dcb\u5df4\u7ec6\u80de+\u5e7c\u7a1a\u6dcb\u5df4\u7ec6\u80de\u226520%\uff09<br> \u25cf \u7b2c33-45\u5929\u9aa8\u9ad3\u7ec6\u80de\u5f62\u6001\u5b66\u68c0\u67e5\u7ed3\u679c\u663e\u793a\u672a\u5b8c\u5168\u7f13\u89e3\uff0cM2\u6216M3\u72b6\u6001\uff08\u539f\u59cb\u6dcb\u5df4\u7ec6\u80de+\u5e7c\u7a1a\u6dcb\u5df4\u7ec6\u80de\u22655\uff05\uff09\u3002 <br> \u25cf t(4; 11)(MLL-AF4)\u6216\u5176\u5b83MLL\u57fa\u56e0\u91cd\u6392\u9633\u6027\u3002 <br> \u25cf \u4f4e\u4e8c\u500d\u4f53\uff08\u67d3\u8272\u4f53\u603b\u8ff0\u226444\uff09\u6216DNA\u6307\u6570\uff08DI\uff09\uff1c0.8\u3002 <br> \u25cf IKZF\u7f3a\u5931\u9633\u6027\u3002 <br> \u25cf \u5b58\u5728MEF2D\u91cd\u6392\u3002 <br> \u25cf \u5b58\u5728TCF3-HLF\/t(17; 19)(q22; p13) \u57fa\u56e0\u91cd\u6392\u3002 <br> \u25cf \u8bf1\u5bfc\u6cbb\u7597\u540e\uff08\u7b2c33-45\u5929\uff09\uff0c\u7eb5\u9694\u7624\u7076\u6ca1\u6709\u7f29\u5c0f\u5230\u6700\u521d\u80bf\u7624\u521d\u80bf\u7624\u4f53\u79ef\u76841\/3\u3002 <br> \u25cf \u8bf1\u5bfc\u6cbb\u7597\u7b2c15-19\u5929MRD\u22651\u00d710-1\uff1b\u6216\u8bf1\u5bfc\u6cbb\u7597\u540e\uff08\u7b2c33-45\u5929\uff09MRD\u22651\u00d710-2\uff1b\u6216\u5de9\u56fa\u6cbb\u7597\u524dMRD\u22651\u00d710-4\u3002 <br> \u25cf \u513f\u7ae5\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08\u4e0d\u5305\u62ec\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\uff09\u7684\u5371\u9669\u5ea6\u5206\u7ec4<br> \u25cf \u4f4e\u5371\u7ec4<br> \u513f\u7ae5\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\uff08FAB\u5206\u578b\u4e3aM3\uff09\uff0c\u53caFAB\u5206\u578b\u4e3aM2b\u3001M4Eo\u6216\u5176\u4ed6\u643a\u5e26\u7b2c16\u53f7\u67d3\u8272\u4f53\u5012\u4f4d\u7684\u60a3\u513f\u3002 <br> \u25cf \u4e2d\u5371\u7ec4<br> \u4e0d\u5c5e\u4e8e\u4f4e\u5371\u7ec4\uff0c\u4e14\u4e0d\u5b58\u5728\u4ee5\u4e0b\u5371\u9669\u56e0\u7d20\uff1a<br> \u25cf \u60a3\u513f\u8bca\u65ad\u4e3a\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\u65f6\u5e74\u9f84\u4e0d\u8d85\u8fc7\u4e00\u5c81\u3002 <br> \u25cf \u8bca\u65ad\u65f6\u767d\u7ec6\u80de\u8ba1\u6570\u5927\u4e8e\u6216\u7b49\u4e8e100 X 109\/L\u3002 <br> \u25cf 7\u53f7\u67d3\u8272\u4f53\u7f3a\u5931\u3002 <br> \u25cf \u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81<br> \u25cf \u6807\u51c6\u65b9\u6848\u4e00\u4e2a\u7597\u7a0b\u4e0d\u7f13\u89e3\u3002 <br> \u25cf \u9ad8\u5371\u7ec4<br> \u5b58\u5728\u4e0a\u8ff0\u4e94\u79cd\u5371\u9669\u56e0\u7d20\u4e2d\u7684\u4efb\u610f\u4e00\u79cd\u3002 <br> \u25cf \u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\u7684\u5371\u9669\u5ea6\u5206\u7ec4<br> \u25cf \u4f4e\u5371\u7ec4\uff1a\u767d\u7ec6\u80de\u8ba1\u6570&lt;10\u00d7109\/L\u3002 <br> \u25cf \u9ad8\u5371\u7ec4\uff1a\u767d\u7ec6\u80de\u8ba1\u6570\u226510\u00d7109\/L\uff0c\u6216\u5b58\u5728FLT3-ITD\u7a81\u53d8\uff0c\u6216\u4f4e\u5371\u7ec4\u7ef4\u6301\u6cbb\u7597\u524d\u672a\u8fbe\u5230\u5206\u5b50\u751f\u7269\u5b66\u7f13\u89e3\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u767d\u8840\u75c5 \u79d1\u666e\u77e5\u8bc6 \u767d\u8840\u75c5\u662f\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u6700\u5e38\u89c1\u7684\u764c\u75c7\uff0c\u51e0\u4e4e\u5360\u4e86\u4e09\u5206\u4e4b\u4e00\u3002 \u5927\u90e8\u5206\u513f\u7ae5\u767d\u8840\u75c5\u662f\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u6027\u767d\u8840\u75c5<span class=\"dots\"> &hellip; 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